What is Lymphoma?
Lymphoma is cancer that begins in cells of the lymph system. The lymph system is part of the immune system, which helps the body fight infection and disease. Because lymph tissue is found all through the body, lymphoma can begin almost anywhere.
Lymphomas are divided into two general types: Hodgkin lymphoma and non-Hodgkin lymphoma. Both Hodgkin lymphoma and non-Hodgkin lymphoma may occur in AIDS patients, but non-Hodgkin lymphoma is more common. When a person with AIDS has non-Hodgkin lymphoma, it is called an AIDS-related lymphoma. The treatment and the chance of a cure depend on the stage and the type of lymphoma.
“Lymphoma is a blood cell cancer. The effected cells are called lymphocytes, a type of white blood cell that helps protect us from infection.” Diffuse Large B-Cell Lymphomas (DLBCL) is the most common type of lymphoma. It has an aggressive (fast growing) behavior and is treated at diagnosis with curative intent.
The word “diffuse” describes the cell pattern. B-cells arise from the bone marrow and mature or differentiate into many cell types that tend to migrate to different areas of the body.
Initial presentation: DLBCL typically presents as a nodal or extranodal mass (outside the lymphatic system) with fast tumor growth associated with systemic symptoms, such as sweats, fatigue, and fever. In about 40% of cases, these lymphomas appear in areas outside lymph nodes, including digestive tract, skin, bone, thyroid, and testes.
What are Clinical Trials?
Clinical trials also called research studies offer high-quality cancer care treatment for qualifying patients. Study treatments may prove to be as good as, or better than the currently approved treatments. By participating in clinical trials, qualifying patients have the chance to help improve cancer treatment for themselves and other cancer patients.
Who do I speak with to get into a Lymphoma clinical trial?
For questions contact:
Suki Subbiah, MD
Open Lymphoma Trial
An Early-Phase Clinical Trial Evaluating ABC294640 in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma or Kaposi Sarcoma
Sponsor: RedHill Biopharma
ClinicalTrials.gov Identifier: NCT02229981
Investigational Product: ABC294640